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Dimerization of the EphA1 Receptor Tyrosine Kinase Transmembrane Domain: Insights into the Mechanism of Receptor Activation
[Image: see text] EphA1 is a receptor tyrosine kinase (RTK) that plays a key role in developmental processes, including guidance of the migration of axons and cells in the nervous system. EphA1, in common with other RTKs, contains an N-terminal extracellular domain, a single transmembrane (TM) α-hel...
Autores principales: | Chavent, Matthieu, Chetwynd, Alan P., Stansfeld, Phillip J., Sansom, Mark S. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298228/ https://www.ncbi.nlm.nih.gov/pubmed/25286141 http://dx.doi.org/10.1021/bi500800x |
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