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Characterization of hepatic enzyme activity in older adults with dementia: potential impact on personalizing pharmacotherapy

OBJECTIVE: To determine the frequency of pharmacogenomic variants and concurrent medications that may alter the efficacy and tolerability of acetylcholinesterase inhibitors (AChEIs). MATERIALS AND METHODS: A multisite cross-sectional study was carried out across four memory care practices in the gre...

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Detalles Bibliográficos
Autores principales: Campbell, Noll L, Skaar, Todd C, Perkins, Anthony J, Gao, Sujuan, Li, Lang, Khan, Babar A, Boustani, Malaz A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298284/
https://www.ncbi.nlm.nih.gov/pubmed/25609939
http://dx.doi.org/10.2147/CIA.S65980