Cargando…

Characterization of hepatic enzyme activity in older adults with dementia: potential impact on personalizing pharmacotherapy

OBJECTIVE: To determine the frequency of pharmacogenomic variants and concurrent medications that may alter the efficacy and tolerability of acetylcholinesterase inhibitors (AChEIs). MATERIALS AND METHODS: A multisite cross-sectional study was carried out across four memory care practices in the gre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Campbell, Noll L, Skaar, Todd C, Perkins, Anthony J, Gao, Sujuan, Li, Lang, Khan, Babar A, Boustani, Malaz A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298284/ https://www.ncbi.nlm.nih.gov/pubmed/25609939 http://dx.doi.org/10.2147/CIA.S65980

Ejemplares similares

Older Primary Care Patients' Attitudes and Willingness to Screen for Dementia
por: Fowler, Nicole R., et al.
Publicado: (2015)

Medication adherence and tolerability of Alzheimer’s disease medications: study protocol for a randomized controlled trial
por: Campbell, Noll L, et al.
Publicado: (2013)

Development of a population‐level prediction model for intensive care unit (ICU) survivorship and mortality in older adults: A population‐based cohort study
por: Khan, Sikandar H., et al.
Publicado: (2023)

Association between Change in the peripheral biomarkers of inflammation, astrocyte activation, and neuroprotection at one week of critical illness and hospital mortality in patients with delirium: A prospective cohort study
por: Khan, Sikandar H., et al.
Publicado: (2023)

Patient characteristics associated with screening positive for Alzheimer’s disease and related dementia
por: Fowler, Nicole R, et al.
Publicado: (2018)

Traits of patients who screen positive for dementia and refuse diagnostic assessment
por: Fowler, Nicole R., et al.
Publicado: (2015)

Dynamic Delirium Severity Trajectories and Their Association With 2-Year Healthcare Utilization and Mortality Outcomes
por: Lindroth, Heidi, et al.
Publicado: (2021)

A gero-informatics tool to enhance the care of hospitalized older adults with cognitive impairment
por: Boustani, Malaz, et al.
Publicado: (2007)

Simultaneous inferences based on empirical Bayes methods and false discovery rates ineQTL data analysis
por: Chakraborty, Arindom, et al.
Publicado: (2013)

Pre-Existing Anxiety and Depression in Injured Older Adults: An Under-Recognized Comorbidity With Major Health Implications
por: Ortiz, Damaris, et al.
Publicado: (2022)

Psychiatric symptoms and their association with sleep disturbances in intensive care unit survivors
por: Wang, Sophia, et al.
Publicado: (2019)

A trauma medical home, evaluating collaborative care for the older injured patient: study protocol for a randomized controlled trial
por: Ortiz, Damaris, et al.
Publicado: (2020)

ASSOCIATION BETWEEN QUALITY OF LIFE AND DEPRESSION IN DYADS OF OLDER PRIMARY CARE PATIENTS AND FAMILY MEMBERS
por: Fowler, Nicole, et al.
Publicado: (2022)

New aQTL SNPs for the CYP2D6 Identified by a Novel Mediation Analysis of Genome-Wide SNP Arrays, Gene Expression Arrays, and CYP2D6 Activity
por: Jiang, Guanglong, et al.
Publicado: (2013)

The Primary Care Physician and the Unsafe Older Drivers
por: Boustani, Malaz
Publicado: (2007)

Improving delirium care in the intensive care unit: The design of a pragmatic study
por: Campbell, Noll L, et al.
Publicado: (2011)

The Indiana University Cognitive Health Outcomes Investigation of the Comparative Effectiveness of dementia screening (CHOICE) study: study protocol for a randomized controlled trial
por: Fowler, Nicole R, et al.
Publicado: (2014)

Examining the benefits and harms of Alzheimer’s disease screening for family members of older adults: study protocol for a randomized controlled trial
por: Fowler, Nicole R., et al.
Publicado: (2020)

Improving Recovery and Outcomes Every Day after the ICU (IMPROVE): study protocol for a randomized controlled trial
por: Wang, Sophia, et al.
Publicado: (2018)

The challenge of supporting care for dementia in primary care
por: Boustani, Malaz, et al.
Publicado: (2007)

Acute Care Utilization by Dementia Caregivers Within Urban Primary Care Practices
por: Schubert, Cathy C., et al.
Publicado: (2008)

Editorial: Deprescribing and Minimizing Use of Anticholinergic Medications
por: Soiza, Roy L., et al.
Publicado: (2021)

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019
por: Khan, Sikandar H., et al.
Publicado: (2020)

Mobile critical care recovery program (m-CCRP) for acute respiratory failure survivors: study protocol for a randomized controlled trial
por: Khan, Sikandar, et al.
Publicado: (2018)

S100 calcium binding protein B as a biomarker of delirium duration in the intensive care unit – an exploratory analysis
por: Khan, Babar A, et al.
Publicado: (2013)

Deprescribing anticholinergics in primary care older adults: Experience from two models and impact on a continuous measure of exposure
por: Campbell, Noll L., et al.
Publicado: (2022)

Decreasing Delirium through Music (DDM) in critically ill, mechanically ventilated patients in the intensive care unit: study protocol for a pilot randomized controlled trial
por: Khan, Sikandar H., et al.
Publicado: (2017)

Delirium severity does not differ between medical and surgical intensive care units after adjusting for medication use
por: Ortiz, Damaris, et al.
Publicado: (2022)

Social Determinants of Health in Community-Dwelling Dementia Patients Aged 65 and Over: Analysis of the 2019 National Health Interview Survey
por: Li, Joanne M., et al.
Publicado: (2023)

Practical clinical tool to monitor dementia symptoms: the HABC-Monitor
por: Monahan, Patrick O, et al.
Publicado: (2012)

Connecting research discovery with care delivery in dementia: the development of the Indianapolis Discovery Network for Dementia
por: Boustani, Malaz A, et al.
Publicado: (2012)

Impact of cholinesterase inhibitors on behavioral and psychological symptoms of Alzheimer’s disease: A meta-analysis
por: Campbell, Noll, et al.
Publicado: (2008)

The Healthy Aging Brain Care (HABC) Monitor: validation of the Patient Self-Report Version of the clinical tool designed to measure and monitor cognitive, functional, and psychological health
por: Monahan, Patrick O, et al.
Publicado: (2014)

Impact of Hospitalization on Antihypertensive Pharmacotherapy among Older Persons
por: Alhawassi, Tariq M., et al.
Publicado: (2015)

Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients: Protocol for a Multisite Randomized Controlled Trial
por: Chodosh, Joshua, et al.
Publicado: (2022)

Delirium and neuropsychological recovery among emergency general surgery survivors (DANE): study protocol for a randomized controlled trial and collaborative care intervention
por: Mohanty, Sanjay, et al.
Publicado: (2023)

Delirium and Neuropsychological Recovery among Emergency General Surgery Survivors (DANE): study protocol for a randomized controlled trial and collaborative care intervention
por: Mohanty, Sanjay, et al.
Publicado: (2023)

Development of Written Materials for Participants in an Alzheimer's Disease and Related Dementias Screening Trial
por: Head, Katharine J, et al.
Publicado: (2022)

Response to depression treatment in the Aging Brain Care Medical Home model
por: LaMantia, Michael A, et al.
Publicado: (2016)

Delirium Superimposed on Dementia Strongly Predicts Worse Outcomes in Older Rehabilitation Inpatients
por: Morandi, Alessandro, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jpuias6pk931ol0gto3oqjlj4o