Cargando…
Suppression of Aggrus/podoplanin-induced platelet aggregation and pulmonary metastasis by a single-chain antibody variable region fragment
Almost all highly metastatic tumor cells possess high platelet aggregating abilities, thereby form large tumor cell-platelet aggregates in the microvasculature. Embolization of tumor cells in the microvasculature is considered to be the first step in metastasis to distant organs. We previously ident...
Autores principales: | Miyata, Kenichi, Takagi, Satoshi, Sato, Shigeo, Morioka, Hiroshi, Shiba, Kiyotaka, Minamisawa, Tamiko, Takami, Miho, Fujita, Naoya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298386/ https://www.ncbi.nlm.nih.gov/pubmed/25132683 http://dx.doi.org/10.1002/cam4.320 |
Ejemplares similares
-
Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis
por: Takagi, Satoshi, et al.
Publicado: (2014) -
Platelets Promote Tumor Growth and Metastasis via Direct Interaction between Aggrus/Podoplanin and CLEC-2
por: Takagi, Satoshi, et al.
Publicado: (2013) -
Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis
por: Sekiguchi, Takaya, et al.
Publicado: (2015) -
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation
por: Miyata, Kenichi, et al.
Publicado: (2017) -
A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis
por: Takemoto, Ai, et al.
Publicado: (2017)