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ATM gene mutations in sporadic breast cancer patients from Brazil

PURPOSE: The Ataxia-telangiectasia mutated (ATM) gene encodes a multifunctional kinase, which is linked to important cellular functions. Women heterozygous for ATM mutations have an estimated relative risk of developing breast cancer of 3.8. However, the pattern of ATM mutations and their role in br...

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Detalles Bibliográficos
Autores principales: Mangone, Flavia Rotea, Miracca, Elisabete C, Feilotter, Harriet E, Mulligan, Lois M, Nagai, Maria Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298590/
https://www.ncbi.nlm.nih.gov/pubmed/25625042
http://dx.doi.org/10.1186/s40064-015-0787-z