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ATM gene mutations in sporadic breast cancer patients from Brazil
PURPOSE: The Ataxia-telangiectasia mutated (ATM) gene encodes a multifunctional kinase, which is linked to important cellular functions. Women heterozygous for ATM mutations have an estimated relative risk of developing breast cancer of 3.8. However, the pattern of ATM mutations and their role in br...
Autores principales: | Mangone, Flavia Rotea, Miracca, Elisabete C, Feilotter, Harriet E, Mulligan, Lois M, Nagai, Maria Aparecida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298590/ https://www.ncbi.nlm.nih.gov/pubmed/25625042 http://dx.doi.org/10.1186/s40064-015-0787-z |
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