The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit

The nucleating activity of the Arp2/3 complex promotes the assembly of branched actin filaments that drive plasma membrane protrusion in migrating cells. Arp2/3 complex binding to nucleation-promoting factors of the WASP and WAVE families was previously thought to be sufficient to increase nucleatin...

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Detalles Bibliográficos
Autores principales: LeClaire, Lawrence L., Rana, Manish, Baumgartner, Martin, Barber, Diane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298681/
https://www.ncbi.nlm.nih.gov/pubmed/25601402
http://dx.doi.org/10.1083/jcb.201404095

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