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Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism

The assembly of the axoneme, the structural scaffold of cilia and flagella, requires translocation of a vast quantity of tubulin into the growing cilium, but the mechanisms that regulate the targeting, quantity, and timing of tubulin transport are largely unknown. In Chlamydomonas, GFP-tagged α-tubu...

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Detalles Bibliográficos
Autores principales: Craft, Julie M., Harris, J. Aaron, Hyman, Sebastian, Kner, Peter, Lechtreck, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298693/
https://www.ncbi.nlm.nih.gov/pubmed/25583998
http://dx.doi.org/10.1083/jcb.201409036