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Cancer systems biology of TCGA SKCM: Efficient detection of genomic drivers in melanoma

We characterized the mutational landscape of human skin cutaneous melanoma (SKCM) using data obtained from The Cancer Genome Atlas (TCGA) project. We analyzed next-generation sequencing data of somatic copy number alterations and somatic mutations in 303 metastatic melanomas. We were able to confirm...

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Detalles Bibliográficos
Autores principales: Guan, Jian, Gupta, Rohit, Filipp, Fabian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298731/
https://www.ncbi.nlm.nih.gov/pubmed/25600636
http://dx.doi.org/10.1038/srep07857