Cargando…

Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy

Radiotherapy (RT) is a central treatment modality for breast cancer patients. The purpose of our study was to investigate the DNA methylation changes in tumors following RT, and to identify epigenetic markers predicting treatment outcome. Paired biopsies from patients with inoperable breast cancer w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Halvorsen, Ann Rita, Helland, Åslaug, Fleischer, Thomas, Haug, Karen Marie, Grenaker Alnæs, Grethe Irene, Nebdal, Daniel, Syljuåsen, Randi G, Touleimat, Nizar, Busato, Florence, Tost, Jörg, Sætersdal, Anna B, Børresen-Dale, Anne-Lise, Kristensen, Vessela, Edvardsen, Hege
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Cancer Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298788/ https://www.ncbi.nlm.nih.gov/pubmed/24658971 http://dx.doi.org/10.1002/ijc.28862

Ejemplares similares

DNA methylation and gene expression patterns in breast cancer progression from in situ carcinoma to invasive carcinoma
por: Fleischer, Thomas, et al.
Publicado: (2013)

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival
por: Fleischer, Thomas, et al.
Publicado: (2016)

Genome‐wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
por: Bjaanæs, Maria Moksnes, et al.
Publicado: (2015)

Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
por: Fleischer, Thomas, et al.
Publicado: (2014)

Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
por: Aure, Miriam Ragle, et al.
Publicado: (2013)

Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer
por: Grenaker Alnaes, Grethe I., et al.
Publicado: (2015)

Intratumor heterogeneity defines treatment‐resistant HER2+ breast tumors
por: Rye, Inga H., et al.
Publicado: (2018)

A systematic comparison of copy number alterations in four types of female cancer
por: Kaveh, Fatemeh, et al.
Publicado: (2016)

Correction to: A systematic comparison of copy number alterations in four types of female cancer
por: Kaveh, Fatemeh, et al.
Publicado: (2018)

Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
por: Klajic, Jovana, et al.
Publicado: (2013)

Genetic polymorphisms in the 5' flanking region of glutathione S-transferase P1 affect promoter methylation
por: Rønneberg, JA, et al.
Publicado: (2005)

Chromosome-wide pharmacogenetics: localisation and linkage disequilibrium of genes coding for ROS metabolism and signalling
por: Edvardsen, H, et al.
Publicado: (2005)

Allele-specific disparity in breast cancer
por: Kaveh, Fatemeh, et al.
Publicado: (2011)

Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
por: Nordgard, Silje H, et al.
Publicado: (2007)

Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas
por: Bjørklund, Sunniva Stordal, et al.
Publicado: (2015)

Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
por: Muggerud, Aslaug Aa, et al.
Publicado: (2010)

Targeting lung cancer through inhibition of checkpoint kinases
por: Syljuåsen, Randi G., et al.
Publicado: (2015)

Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
por: Bjaanæs, Maria Moksnes, et al.
Publicado: (2014)

Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
por: Edvardsen, Hege, et al.
Publicado: (2007)

Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma
por: Bjørklund, Sunniva Stordal, et al.
Publicado: (2017)

Multilocus analysis of SNP and metabolic data within a given pathway
por: Kristensen, Vessela N, et al.
Publicado: (2006)

Mutations for the people
por: Kristensen, Vessela, et al.
Publicado: (2010)

ATM variants and cancer risk in breast cancer patients from Southern Finland
por: Tommiska, Johanna, et al.
Publicado: (2006)

Fibroblast Growth Factor Receptor 3 (FGFR3)–Analyses of the S249C Mutation and Protein Expression in Primary Cervical Carcinomas
por: Dai, Haiyan, et al.
Publicado: (2001)

DNA methylation at enhancers identifies distinct breast cancer lineages
por: Fleischer, Thomas, et al.
Publicado: (2017)

Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
por: Haakensen, Vilde D, et al.
Publicado: (2011)

Identification of microRNAs involved in pathways which characterize the expression subtypes of NSCLC
por: Halvorsen, Ann Rita, et al.
Publicado: (2019)

miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer
por: Lindholm, Evita Maria, et al.
Publicado: (2019)

Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN
por: Borge, Kaja S., et al.
Publicado: (2015)

Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity
por: Dannenfelser, Ruth, et al.
Publicado: (2017)

Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
por: Aure, Miriam Ragle, et al.
Publicado: (2021)

The immune microenvironment in non‐small cell lung cancer is predictive of prognosis after surgery
por: Öjlert, Åsa Kristina, et al.
Publicado: (2019)

PathTracer: High-sensitivity detection of differential pathway activity in tumours
por: Nygård, Ståle, et al.
Publicado: (2019)

Profiling of microRNAs in tumor interstitial fluid of breast tumors – a novel resource to identify biomarkers for prognostic classification and detection of cancer
por: Halvorsen, Ann Rita, et al.
Publicado: (2016)

Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
por: Joshi, Himanshu, et al.
Publicado: (2012)

Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
por: Umu, Sinan U, et al.
Publicado: (2022)

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
por: Halvorsen, Ann R., et al.
Publicado: (2016)

Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer
por: Yoshimura, Noriko, et al.
Publicado: (2004)

Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
por: Solvang, Hiroko K, et al.
Publicado: (2011)

NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
por: Fu, Yi-Ping, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_1ole9itg6ock6se0dhvtl28883