In Vivo Imaging of Mouse Tumors by a Lipidated Cathepsin S Substrate**

The synthesis and evaluation of two cathepsin S-specific probes is described. For long-term retention of the probe at the target site and a high signal-to-noise ratio, we introduced a lipidation approach via the simple attachment of palmitoic acid to the reporter. After cathepsin S-specific cleavage...

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Detalles Bibliográficos
Autores principales: Hu, Hai-Yu, Vats, Divya, Vizovisek, Matej, Kramer, Lovro, Germanier, Catherine, Wendt, K Ulrich, Rudin, Markus, Turk, Boris, Plettenburg, Oliver, Schultz, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298799/
https://www.ncbi.nlm.nih.gov/pubmed/24888522
http://dx.doi.org/10.1002/anie.201310979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298799/
https://www.ncbi.nlm.nih.gov/pubmed/24888522
http://dx.doi.org/10.1002/anie.201310979

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