Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4

A crucial step in the development of therapeutic monoclonal antibodies is the selection of robust pharmaceutical candidates and screening of efficacious protein formulations to increase the resistance toward physicochemical degradation and aggregation during processing and storage. Here, we introduc...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Xinsheng, Langkilde, Annette E, Thorolfsson, Matthias, Rasmussen, Hanne B, Vestergaard, Bente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298811/
https://www.ncbi.nlm.nih.gov/pubmed/24700358
http://dx.doi.org/10.1002/jps.23964

Ejemplares similares

Ejemplares similares