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Isolated pauci-immune pulmonary capillaritis
A young house wife presented with low grade fever, cough, haemoptysis and SOB of unknown aetiology for 40 days duration. Respiratory system examination revealed diffuse crepts and rhonchi. Other organ system examination did not reveal any abnormality. X-ray chest PA view and CT thorax showed diffuse...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298921/ https://www.ncbi.nlm.nih.gov/pubmed/25624599 http://dx.doi.org/10.4103/0970-2113.148453 |
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author | Mehrotra, Ashok Kumar Gupta, Prahlad Rai Khublani, Trilok Kumar Anupam, Soni, Shridha Feroz, Asif |
author_facet | Mehrotra, Ashok Kumar Gupta, Prahlad Rai Khublani, Trilok Kumar Anupam, Soni, Shridha Feroz, Asif |
author_sort | Mehrotra, Ashok Kumar |
collection | PubMed |
description | A young house wife presented with low grade fever, cough, haemoptysis and SOB of unknown aetiology for 40 days duration. Respiratory system examination revealed diffuse crepts and rhonchi. Other organ system examination did not reveal any abnormality. X-ray chest PA view and CT thorax showed diffuse bilateral necrotising nodular lesions of various sizes with small pleural effusion. She also had low resting oxygen saturation with falling haematocrit. Her Serum was week positive for p-ANCA and negative for MPO-ANCA. Bronchoscopy revealed continuous bloody aspirates. We could not isolate any organisms in any of the specimens from her and she was unresponsive to any of the antibiotics either. Based on the clinical, laboratory data, radiological features and positive outcome to pulse therapy of methylprednisolone and cyclophosphamide, she was diagnosed as a case of IPIPC. |
format | Online Article Text |
id | pubmed-4298921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42989212015-01-26 Isolated pauci-immune pulmonary capillaritis Mehrotra, Ashok Kumar Gupta, Prahlad Rai Khublani, Trilok Kumar Anupam, Soni, Shridha Feroz, Asif Lung India Case Report A young house wife presented with low grade fever, cough, haemoptysis and SOB of unknown aetiology for 40 days duration. Respiratory system examination revealed diffuse crepts and rhonchi. Other organ system examination did not reveal any abnormality. X-ray chest PA view and CT thorax showed diffuse bilateral necrotising nodular lesions of various sizes with small pleural effusion. She also had low resting oxygen saturation with falling haematocrit. Her Serum was week positive for p-ANCA and negative for MPO-ANCA. Bronchoscopy revealed continuous bloody aspirates. We could not isolate any organisms in any of the specimens from her and she was unresponsive to any of the antibiotics either. Based on the clinical, laboratory data, radiological features and positive outcome to pulse therapy of methylprednisolone and cyclophosphamide, she was diagnosed as a case of IPIPC. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4298921/ /pubmed/25624599 http://dx.doi.org/10.4103/0970-2113.148453 Text en Copyright: © Lung India http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mehrotra, Ashok Kumar Gupta, Prahlad Rai Khublani, Trilok Kumar Anupam, Soni, Shridha Feroz, Asif Isolated pauci-immune pulmonary capillaritis |
title | Isolated pauci-immune pulmonary capillaritis |
title_full | Isolated pauci-immune pulmonary capillaritis |
title_fullStr | Isolated pauci-immune pulmonary capillaritis |
title_full_unstemmed | Isolated pauci-immune pulmonary capillaritis |
title_short | Isolated pauci-immune pulmonary capillaritis |
title_sort | isolated pauci-immune pulmonary capillaritis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298921/ https://www.ncbi.nlm.nih.gov/pubmed/25624599 http://dx.doi.org/10.4103/0970-2113.148453 |
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