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Computational cancer biology: education is a natural key to many locks
BACKGROUND: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and stat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298945/ https://www.ncbi.nlm.nih.gov/pubmed/25588624 http://dx.doi.org/10.1186/s12885-014-1002-2 |
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author | Emmert-Streib, Frank Zhang, Shu-Dong Hamilton, Peter |
author_facet | Emmert-Streib, Frank Zhang, Shu-Dong Hamilton, Peter |
author_sort | Emmert-Streib, Frank |
collection | PubMed |
description | BACKGROUND: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and statistical analysis methods are required that need to be developed in a problem-directed manner. DISCUSSION: For this reason, computational cancer biology aims to fill this gap. Unfortunately, computational cancer biology is not yet fully recognized as a coequal field in oncology, leading to a delay in its maturation and, as an immediate consequence, an under-exploration of high-throughput data for translational research. SUMMARY: Here we argue that this imbalance, favoring ’wet lab-based activities’, will be naturally rectified over time, if the next generation of scientists receives an academic education that provides a fair and competent introduction to computational biology and its manifold capabilities. Furthermore, we discuss a number of local educational provisions that can be implemented on university level to help in facilitating the process of harmonization. |
format | Online Article Text |
id | pubmed-4298945 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42989452015-01-21 Computational cancer biology: education is a natural key to many locks Emmert-Streib, Frank Zhang, Shu-Dong Hamilton, Peter BMC Cancer Debate BACKGROUND: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and statistical analysis methods are required that need to be developed in a problem-directed manner. DISCUSSION: For this reason, computational cancer biology aims to fill this gap. Unfortunately, computational cancer biology is not yet fully recognized as a coequal field in oncology, leading to a delay in its maturation and, as an immediate consequence, an under-exploration of high-throughput data for translational research. SUMMARY: Here we argue that this imbalance, favoring ’wet lab-based activities’, will be naturally rectified over time, if the next generation of scientists receives an academic education that provides a fair and competent introduction to computational biology and its manifold capabilities. Furthermore, we discuss a number of local educational provisions that can be implemented on university level to help in facilitating the process of harmonization. BioMed Central 2015-01-15 /pmc/articles/PMC4298945/ /pubmed/25588624 http://dx.doi.org/10.1186/s12885-014-1002-2 Text en © Emmert-Streib et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Debate Emmert-Streib, Frank Zhang, Shu-Dong Hamilton, Peter Computational cancer biology: education is a natural key to many locks |
title | Computational cancer biology: education is a natural key to many locks |
title_full | Computational cancer biology: education is a natural key to many locks |
title_fullStr | Computational cancer biology: education is a natural key to many locks |
title_full_unstemmed | Computational cancer biology: education is a natural key to many locks |
title_short | Computational cancer biology: education is a natural key to many locks |
title_sort | computational cancer biology: education is a natural key to many locks |
topic | Debate |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298945/ https://www.ncbi.nlm.nih.gov/pubmed/25588624 http://dx.doi.org/10.1186/s12885-014-1002-2 |
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