Cargando…

Computational cancer biology: education is a natural key to many locks

BACKGROUND: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and stat...

Descripción completa

Detalles Bibliográficos
Autores principales: Emmert-Streib, Frank, Zhang, Shu-Dong, Hamilton, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298945/
https://www.ncbi.nlm.nih.gov/pubmed/25588624
http://dx.doi.org/10.1186/s12885-014-1002-2
_version_ 1782353328921903104
author Emmert-Streib, Frank
Zhang, Shu-Dong
Hamilton, Peter
author_facet Emmert-Streib, Frank
Zhang, Shu-Dong
Hamilton, Peter
author_sort Emmert-Streib, Frank
collection PubMed
description BACKGROUND: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and statistical analysis methods are required that need to be developed in a problem-directed manner. DISCUSSION: For this reason, computational cancer biology aims to fill this gap. Unfortunately, computational cancer biology is not yet fully recognized as a coequal field in oncology, leading to a delay in its maturation and, as an immediate consequence, an under-exploration of high-throughput data for translational research. SUMMARY: Here we argue that this imbalance, favoring ’wet lab-based activities’, will be naturally rectified over time, if the next generation of scientists receives an academic education that provides a fair and competent introduction to computational biology and its manifold capabilities. Furthermore, we discuss a number of local educational provisions that can be implemented on university level to help in facilitating the process of harmonization.
format Online
Article
Text
id pubmed-4298945
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-42989452015-01-21 Computational cancer biology: education is a natural key to many locks Emmert-Streib, Frank Zhang, Shu-Dong Hamilton, Peter BMC Cancer Debate BACKGROUND: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and statistical analysis methods are required that need to be developed in a problem-directed manner. DISCUSSION: For this reason, computational cancer biology aims to fill this gap. Unfortunately, computational cancer biology is not yet fully recognized as a coequal field in oncology, leading to a delay in its maturation and, as an immediate consequence, an under-exploration of high-throughput data for translational research. SUMMARY: Here we argue that this imbalance, favoring ’wet lab-based activities’, will be naturally rectified over time, if the next generation of scientists receives an academic education that provides a fair and competent introduction to computational biology and its manifold capabilities. Furthermore, we discuss a number of local educational provisions that can be implemented on university level to help in facilitating the process of harmonization. BioMed Central 2015-01-15 /pmc/articles/PMC4298945/ /pubmed/25588624 http://dx.doi.org/10.1186/s12885-014-1002-2 Text en © Emmert-Streib et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Debate
Emmert-Streib, Frank
Zhang, Shu-Dong
Hamilton, Peter
Computational cancer biology: education is a natural key to many locks
title Computational cancer biology: education is a natural key to many locks
title_full Computational cancer biology: education is a natural key to many locks
title_fullStr Computational cancer biology: education is a natural key to many locks
title_full_unstemmed Computational cancer biology: education is a natural key to many locks
title_short Computational cancer biology: education is a natural key to many locks
title_sort computational cancer biology: education is a natural key to many locks
topic Debate
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298945/
https://www.ncbi.nlm.nih.gov/pubmed/25588624
http://dx.doi.org/10.1186/s12885-014-1002-2
work_keys_str_mv AT emmertstreibfrank computationalcancerbiologyeducationisanaturalkeytomanylocks
AT zhangshudong computationalcancerbiologyeducationisanaturalkeytomanylocks
AT hamiltonpeter computationalcancerbiologyeducationisanaturalkeytomanylocks