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GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivity when we want to detect specific molecules in bio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299039/ https://www.ncbi.nlm.nih.gov/pubmed/25474375 http://dx.doi.org/10.3390/s141222785 |
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author | Chopard, Tony Lacour, Vivien Leblois, Therese |
author_facet | Chopard, Tony Lacour, Vivien Leblois, Therese |
author_sort | Chopard, Tony |
collection | PubMed |
description | This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivity when we want to detect specific molecules in biological fields. These developments constitute an obstacle to the early diagnosis of diseases. An alternative is the design of coupled structures. In this study, the device is based on the piezoelectric excitation and detection of two GaAs microstructures vibrating in antisymmetric modes. GaAs is a crystal which has the advantage to be micromachined easily using typical clean room processes. Moreover, we showed its high potential in direct biofunctionalisation for use in the biological field. A specific design of the device was performed to improve the detection at low mass and an original detection method has been developed. The principle is to exploit the variation in amplitude at the initial resonance frequency which has in the vicinity of weak added mass the greatest slope. Therefore, we get a very good resolution for an infinitely weak mass: relative voltage variation of 8%/1 fg. The analysis is based on results obtained by finite element simulation. |
format | Online Article Text |
id | pubmed-4299039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-42990392015-01-26 GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection Chopard, Tony Lacour, Vivien Leblois, Therese Sensors (Basel) Article This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivity when we want to detect specific molecules in biological fields. These developments constitute an obstacle to the early diagnosis of diseases. An alternative is the design of coupled structures. In this study, the device is based on the piezoelectric excitation and detection of two GaAs microstructures vibrating in antisymmetric modes. GaAs is a crystal which has the advantage to be micromachined easily using typical clean room processes. Moreover, we showed its high potential in direct biofunctionalisation for use in the biological field. A specific design of the device was performed to improve the detection at low mass and an original detection method has been developed. The principle is to exploit the variation in amplitude at the initial resonance frequency which has in the vicinity of weak added mass the greatest slope. Therefore, we get a very good resolution for an infinitely weak mass: relative voltage variation of 8%/1 fg. The analysis is based on results obtained by finite element simulation. MDPI 2014-12-02 /pmc/articles/PMC4299039/ /pubmed/25474375 http://dx.doi.org/10.3390/s141222785 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chopard, Tony Lacour, Vivien Leblois, Therese GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection |
title | GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection |
title_full | GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection |
title_fullStr | GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection |
title_full_unstemmed | GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection |
title_short | GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection |
title_sort | gaas coupled micro resonators with enhanced sensitive mass detection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299039/ https://www.ncbi.nlm.nih.gov/pubmed/25474375 http://dx.doi.org/10.3390/s141222785 |
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