Cargando…

GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection

This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivity when we want to detect specific molecules in bio...

Descripción completa

Detalles Bibliográficos
Autores principales: Chopard, Tony, Lacour, Vivien, Leblois, Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299039/
https://www.ncbi.nlm.nih.gov/pubmed/25474375
http://dx.doi.org/10.3390/s141222785
_version_ 1782353343585189888
author Chopard, Tony
Lacour, Vivien
Leblois, Therese
author_facet Chopard, Tony
Lacour, Vivien
Leblois, Therese
author_sort Chopard, Tony
collection PubMed
description This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivity when we want to detect specific molecules in biological fields. These developments constitute an obstacle to the early diagnosis of diseases. An alternative is the design of coupled structures. In this study, the device is based on the piezoelectric excitation and detection of two GaAs microstructures vibrating in antisymmetric modes. GaAs is a crystal which has the advantage to be micromachined easily using typical clean room processes. Moreover, we showed its high potential in direct biofunctionalisation for use in the biological field. A specific design of the device was performed to improve the detection at low mass and an original detection method has been developed. The principle is to exploit the variation in amplitude at the initial resonance frequency which has in the vicinity of weak added mass the greatest slope. Therefore, we get a very good resolution for an infinitely weak mass: relative voltage variation of 8%/1 fg. The analysis is based on results obtained by finite element simulation.
format Online
Article
Text
id pubmed-4299039
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-42990392015-01-26 GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection Chopard, Tony Lacour, Vivien Leblois, Therese Sensors (Basel) Article This work demonstrates the improvement of mass detection sensitivity and time response using a simple sensor structure. Indeed, complicated technological processes leading to very brittle sensing structures are often required to reach high sensitivity when we want to detect specific molecules in biological fields. These developments constitute an obstacle to the early diagnosis of diseases. An alternative is the design of coupled structures. In this study, the device is based on the piezoelectric excitation and detection of two GaAs microstructures vibrating in antisymmetric modes. GaAs is a crystal which has the advantage to be micromachined easily using typical clean room processes. Moreover, we showed its high potential in direct biofunctionalisation for use in the biological field. A specific design of the device was performed to improve the detection at low mass and an original detection method has been developed. The principle is to exploit the variation in amplitude at the initial resonance frequency which has in the vicinity of weak added mass the greatest slope. Therefore, we get a very good resolution for an infinitely weak mass: relative voltage variation of 8%/1 fg. The analysis is based on results obtained by finite element simulation. MDPI 2014-12-02 /pmc/articles/PMC4299039/ /pubmed/25474375 http://dx.doi.org/10.3390/s141222785 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chopard, Tony
Lacour, Vivien
Leblois, Therese
GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
title GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
title_full GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
title_fullStr GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
title_full_unstemmed GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
title_short GaAs Coupled Micro Resonators with Enhanced Sensitive Mass Detection
title_sort gaas coupled micro resonators with enhanced sensitive mass detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299039/
https://www.ncbi.nlm.nih.gov/pubmed/25474375
http://dx.doi.org/10.3390/s141222785
work_keys_str_mv AT chopardtony gaascoupledmicroresonatorswithenhancedsensitivemassdetection
AT lacourvivien gaascoupledmicroresonatorswithenhancedsensitivemassdetection
AT lebloistherese gaascoupledmicroresonatorswithenhancedsensitivemassdetection