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Genetically diverse mice are novel and valuable models of age-associated susceptibility to Mycobacterium tuberculosis

BACKGROUND: Tuberculosis, the disease due to Mycobacterium tuberculosis, is an important cause of morbidity and mortality in the elderly. Use of mouse models may accelerate insight into the disease and tests of therapies since mice age thirty times faster than humans. However, the majority of TB res...

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Detalles Bibliográficos
Autores principales: Harrison, David E, Astle, Clinton M, Niazi, M Khalid Khan, Major, Samuel, Beamer, Gillian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299371/
https://www.ncbi.nlm.nih.gov/pubmed/25606048
http://dx.doi.org/10.1186/s12979-014-0024-6