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Constant rate of p53 tetramerization in response to DNA damage controls the p53 response

The dynamics of the tumor suppressor protein p53 have been previously investigated in single cells using fluorescently tagged p53. Such approach reports on the total abundance of p53 but does not provide a measure for functional p53. We used fluorescent protein-fragment complementation assay (PCA) t...

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Detalles Bibliográficos
Autores principales:	Gaglia, Giorgio, Lahav, Galit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299375/ https://www.ncbi.nlm.nih.gov/pubmed/25344068 http://dx.doi.org/10.15252/msb.20145168

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