Cargando…

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs

Most complex disease-associated genetic variants are located in non-coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis-regulatory impact (cis-rSNPs). We used AE mapping...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adoue, Veronique, Schiavi, Alicia, Light, Nicholas, Almlöf, Jonas Carlsson, Lundmark, Per, Ge, Bing, Kwan, Tony, Caron, Maxime, Rönnblom, Lars, Wang, Chuan, Chen, Shu-Huang, Goodall, Alison H, Cambien, Francois, Deloukas, Panos, Ouwehand, Willem H, Syvänen, Ann-Christine, Pastinen, Tomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299376/ https://www.ncbi.nlm.nih.gov/pubmed/25326100 http://dx.doi.org/10.15252/msb.20145114

Ejemplares similares

Single Nucleotide Polymorphisms with Cis-Regulatory Effects on Long Non-Coding Transcripts in Human Primary Monocytes
por: Carlsson Almlöf, Jonas, et al.
Publicado: (2014)

Powerful Identification of Cis-regulatory SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression
por: Almlöf, Jonas Carlsson, et al.
Publicado: (2012)

Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome
por: Cotton, Allison M, et al.
Publicado: (2013)

Human genetics in full resolution
por: Schiavi, Alicia, et al.
Publicado: (2011)

Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression
por: Greliche, Nicolas, et al.
Publicado: (2012)

Correction: Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression
por: Greliche, Nicolas, et al.
Publicado: (2012)

Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
por: Lundtoft, Christian, et al.
Publicado: (2020)

Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
por: Imgenberg-Kreuz, Juliana, et al.
Publicado: (2019)

Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells
por: Morin, Andréanne, et al.
Publicado: (2016)

Genome-Wide Haplotype Analysis of Cis Expression Quantitative Trait Loci in Monocytes
por: Garnier, Sophie, et al.
Publicado: (2013)

Global identification of conserved post-transcriptional regulatory programs in trypanosomatids
por: Najafabadi, Hamed S., et al.
Publicado: (2013)

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5
por: Sigurdsson, Snaevar, et al.
Publicado: (2008)

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes
por: Imgenberg-Kreuz, Juliana, et al.
Publicado: (2016)

Exploring rare and low-frequency variants in the Saguenay–Lac-Saint-Jean population identified genes associated with asthma and allergy traits
por: Morin, Andréanne, et al.
Publicado: (2018)

Computational Analysis of Whole-Genome Differential Allelic Expression Data in Human
por: Wagner, James R., et al.
Publicado: (2010)

Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
por: Almlöf, Jonas Carlsson, et al.
Publicado: (2019)

Population differentiation in allele frequencies of obesity-associated SNPs
por: Mao, Linyong, et al.
Publicado: (2017)

Accuracy of Programs for the Determination of Human Leukocyte Antigen Alleles from Next-Generation Sequencing Data
por: Larjo, Antti, et al.
Publicado: (2017)

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array
por: Marzouka, Nour-al-dain, et al.
Publicado: (2016)

Contributions of de novo variants to systemic lupus erythematosus
por: Almlöf, Jonas Carlsson, et al.
Publicado: (2020)

Genotype-Based Test in Mapping Cis-Regulatory Variants from Allele-Specific Expression Data
por: Lefebvre, Jean Francois, et al.
Publicado: (2012)

Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease
por: Ding, Keyue, et al.
Publicado: (2011)

Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
por: Allum, Fiona, et al.
Publicado: (2015)

Lineage-specific SNPs for genotyping of Mycobacterium tuberculosis clinical isolates
por: Dou, Horng-Yunn, et al.
Publicado: (2017)

Haplotyping SNPs for allele-specific gene editing of the expanded huntingtin allele using long-read sequencing
por: Fang, Li, et al.
Publicado: (2022)

Haplotyping SNPs for allele-specific gene editing of the expanded huntingtin allele using long-read sequencing
por: Fang, Li, et al.
Publicado: (2023)

Prediction of HLA Class II Alleles Using SNPs in an African Population
por: Ayele, Fasil Tekola, et al.
Publicado: (2012)

TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance
por: Valentini, Samuel, et al.
Publicado: (2021)

Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation
por: Busche, Stephan, et al.
Publicado: (2015)

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
por: Imgenberg-Kreuz, Juliana, et al.
Publicado: (2018)

The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
por: Hagberg, Niklas, et al.
Publicado: (2018)

Correction: Prediction of HLA Class II Alleles Using SNPs in an African Population
por: Ayele, Fasil Tekola, et al.
Publicado: (2012)

Analysis of elite variety tag SNPs reveals an important allele in upland rice
por: Lyu, Jun, et al.
Publicado: (2013)

Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson's Disease
por: Zhu, Zuobin, et al.
Publicado: (2015)

ANANASTRA: annotation and enrichment analysis of allele-specific transcription factor binding at SNPs
por: Boytsov, Alexandr, et al.
Publicado: (2022)

Conserved expression of transposon-derived non-coding transcripts in primate stem cells
por: Ramsay, LeeAnn, et al.
Publicado: (2017)

Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes
por: Caron, Maxime, et al.
Publicado: (2018)

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes
por: Lindqvist, C. Mårten, et al.
Publicado: (2016)

Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements
por: Allum, Fiona, et al.
Publicado: (2019)

Maps of open chromatin highlight cell type–restricted patterns of regulatory sequence variation at hematological trait loci
por: Paul, Dirk S., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_m7731r6vscteat4optce9059hr