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Computational modeling suggests dimerization of equine infectious anemia virus Rev is required for RNA binding
BACKGROUND: The lentiviral Rev protein mediates nuclear export of intron-containing viral RNAs that encode structural proteins or serve as the viral genome. Following translation, HIV-1 Rev localizes to the nucleus and binds its cognate sequence, termed the Rev-responsive element (RRE), in incomplet...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299382/ https://www.ncbi.nlm.nih.gov/pubmed/25533001 http://dx.doi.org/10.1186/s12977-014-0115-7 |