Synthetic biology: the many facets of T7 RNA polymerase

Split T7 RNA polymerase provides new avenues for creating synthetic gene circuits that are decoupled from host regulatory processes—but how many times can this enzyme be split, yet retain function? New research by Voigt and colleagues (Segall-Shapiro et al, 2014) indicates that it may be more than y...

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Detalles Bibliográficos
Autores principales: Shis, David L, Bennett, Matthew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299499/
https://www.ncbi.nlm.nih.gov/pubmed/25080495
http://dx.doi.org/10.15252/msb.20145492
Descripción
Sumario:Split T7 RNA polymerase provides new avenues for creating synthetic gene circuits that are decoupled from host regulatory processes—but how many times can this enzyme be split, yet retain function? New research by Voigt and colleagues (Segall-Shapiro et al, 2014) indicates that it may be more than you think.

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