Synthetic biology: the many facets of T7 RNA polymerase

Split T7 RNA polymerase provides new avenues for creating synthetic gene circuits that are decoupled from host regulatory processes—but how many times can this enzyme be split, yet retain function? New research by Voigt and colleagues (Segall-Shapiro et al, 2014) indicates that it may be more than y...

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Detalles Bibliográficos
Autores principales: Shis, David L, Bennett, Matthew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299499/
https://www.ncbi.nlm.nih.gov/pubmed/25080495
http://dx.doi.org/10.15252/msb.20145492
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author Shis, David L
Bennett, Matthew R
author_facet Shis, David L
Bennett, Matthew R
author_sort Shis, David L
collection PubMed
description Split T7 RNA polymerase provides new avenues for creating synthetic gene circuits that are decoupled from host regulatory processes—but how many times can this enzyme be split, yet retain function? New research by Voigt and colleagues (Segall-Shapiro et al, 2014) indicates that it may be more than you think.
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spelling pubmed-42994992015-01-20 Synthetic biology: the many facets of T7 RNA polymerase Shis, David L Bennett, Matthew R Mol Syst Biol News & Views Split T7 RNA polymerase provides new avenues for creating synthetic gene circuits that are decoupled from host regulatory processes—but how many times can this enzyme be split, yet retain function? New research by Voigt and colleagues (Segall-Shapiro et al, 2014) indicates that it may be more than you think. Blackwell Publishing Ltd 2014-07-30 /pmc/articles/PMC4299499/ /pubmed/25080495 http://dx.doi.org/10.15252/msb.20145492 Text en © 2014 The Authors. Published under the terms of the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News & Views
Shis, David L
Bennett, Matthew R
Synthetic biology: the many facets of T7 RNA polymerase
title Synthetic biology: the many facets of T7 RNA polymerase
title_full Synthetic biology: the many facets of T7 RNA polymerase
title_fullStr Synthetic biology: the many facets of T7 RNA polymerase
title_full_unstemmed Synthetic biology: the many facets of T7 RNA polymerase
title_short Synthetic biology: the many facets of T7 RNA polymerase
title_sort synthetic biology: the many facets of t7 rna polymerase
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299499/
https://www.ncbi.nlm.nih.gov/pubmed/25080495
http://dx.doi.org/10.15252/msb.20145492
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