Specific capture and detection of Staphylococcus aureus with high-affinity modified aptamers to cell surface components

Slow off-rate modified aptamer (SOMAmer) reagents were generated to several Staphylococcus aureus cell surface-associated proteins via SELEX with multiple modified DNA libraries using purified recombinant or native proteins. High-affinity binding agents with sub-nanomolar K(d)'s were obtained f...

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Detalles Bibliográficos
Autores principales: Baumstummler, A, Lehmann, D, Janjic, N, Ochsner, UA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299505/
https://www.ncbi.nlm.nih.gov/pubmed/24935714
http://dx.doi.org/10.1111/lam.12295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299505/
https://www.ncbi.nlm.nih.gov/pubmed/24935714
http://dx.doi.org/10.1111/lam.12295

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