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Glyceraldehyde-derived pyridinium (GLAP) evokes oxidative stress and inflammatory and thrombogenic reactions in endothelial cells via the interaction with RAGE

BACKGROUND: We have previously shown that serum levels of glyceraldehyde-derived advanced glycation end products (Gly-AGEs) are elevated under oxidative stress and/or diabetic conditions and associated with insulin resistance, endothelial dysfunction and vascular inflammation in humans. Further, Gly...

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Detalles Bibliográficos
Autores principales: Matsui, Takanori, Oda, Eriko, Higashimoto, Yuichiro, Yamagishi, Sho-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299541/
https://www.ncbi.nlm.nih.gov/pubmed/25582325
http://dx.doi.org/10.1186/s12933-014-0162-3