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Short-Term Comparative Study of the Cyclophosphamide Genotoxicity Administered Free and Liposome-Encapsulated in Mice

BACKGROUND: Cyclophosphamide (CYP) is used to treat a wide range of human tumors. However, the mutagenic effect of CYP is still the primary limitation for wider applications to treat a variety of human malignancies. It has been reported that CYP entrapped in liposomes reduces non-specific toxicity a...

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Detalles Bibliográficos
Autor principal: Abdella, Ehab Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Research Center, Shahid Beheshti University of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299619/
https://www.ncbi.nlm.nih.gov/pubmed/25628821