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Genetic variability of microRNA regulome in human

MicroRNAs are currently being extensively studied due to their important role as post-transcriptional regulators. During miRNA biogenesis, precursors undergo two cleavage steps performed by Drosha-DGCR8 (Microprocessor) cleaving of pri-miRNA to produce pre-miRNA and Dicer-mediated cleaving to create...

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Detalles Bibliográficos
Autores principales: Obsteter, Jana, Dovc, Peter, Kunej, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299713/
https://www.ncbi.nlm.nih.gov/pubmed/25629077
http://dx.doi.org/10.1002/mgg3.110