Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds

WNT10A is a signaling molecule involved in tooth development, and WNT10A defects are associated with tooth agenesis. We characterized Wnt10a null mice generated by the knockout mouse project (KOMP) and six families with WNT10A mutations, including a novel p.Arg104Cys defect, in the absence of EDA,ED...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Wang, Shih-Kai, Choi, Murim, Reid, Bryan M, Hu, Yuanyuan, Lee, Yuan-Ling, Herzog, Curtis R, Kim-Berman, Hera, Lee, Moses, Benke, Paul J, Kent Lloyd, K C, Simmer, James P, Hu, Jan C-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299714/
https://www.ncbi.nlm.nih.gov/pubmed/25629078
http://dx.doi.org/10.1002/mgg3.111

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