Aberrant Hypermethylation of Aldehyde Dehydrogenase 2 Promoter Upstream Sequence in Rats with Experimental Myocardial Infarction

Background. Aldehyde dehydrogenase 2 (ALDH2) plays a crucial role in myocardial protection against ischemia. Downregulation of ALDH2 was evidenced after myocardial infarction and the underlying mechanism is not fully understood. DNA methylation can regulate gene transcription in epigenetic level. We...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Shen, Cheng, Diao, Lei, Yang, Zhiyin, Fan, Fan, Wang, Cong, Liu, Xiangwei, Sun, Xiaolei, Dong, Zhen, Zhu, Hong, Ma, Xin, Cao, Quan, Zhao, Xiaona, Ma, Duan, Zou, Yunzeng, Hu, Kai, Sun, Aijun, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299765/
https://www.ncbi.nlm.nih.gov/pubmed/25629048
http://dx.doi.org/10.1155/2015/503692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299765/
https://www.ncbi.nlm.nih.gov/pubmed/25629048
http://dx.doi.org/10.1155/2015/503692

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