Cargando…

Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment

Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis r...

Descripción completa

Detalles Bibliográficos
Autores principales: Mouchtouris, Nikolaos, Chalouhi, Nohra, Chitale, Ameet, Starke, Robert M., Tjoumakaris, Stavropoula I., Rosenwasser, Robert H., Jabbour, Pascal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300037/
https://www.ncbi.nlm.nih.gov/pubmed/25629087
http://dx.doi.org/10.1155/2015/808314
_version_ 1782353473115783168
author Mouchtouris, Nikolaos
Chalouhi, Nohra
Chitale, Ameet
Starke, Robert M.
Tjoumakaris, Stavropoula I.
Rosenwasser, Robert H.
Jabbour, Pascal M.
author_facet Mouchtouris, Nikolaos
Chalouhi, Nohra
Chitale, Ameet
Starke, Robert M.
Tjoumakaris, Stavropoula I.
Rosenwasser, Robert H.
Jabbour, Pascal M.
author_sort Mouchtouris, Nikolaos
collection PubMed
description Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics.
format Online
Article
Text
id pubmed-4300037
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43000372015-01-27 Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment Mouchtouris, Nikolaos Chalouhi, Nohra Chitale, Ameet Starke, Robert M. Tjoumakaris, Stavropoula I. Rosenwasser, Robert H. Jabbour, Pascal M. ScientificWorldJournal Review Article Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics. Hindawi Publishing Corporation 2015 2015-01-05 /pmc/articles/PMC4300037/ /pubmed/25629087 http://dx.doi.org/10.1155/2015/808314 Text en Copyright © 2015 Nikolaos Mouchtouris et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mouchtouris, Nikolaos
Chalouhi, Nohra
Chitale, Ameet
Starke, Robert M.
Tjoumakaris, Stavropoula I.
Rosenwasser, Robert H.
Jabbour, Pascal M.
Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
title Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
title_full Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
title_fullStr Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
title_full_unstemmed Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
title_short Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
title_sort management of cerebral cavernous malformations: from diagnosis to treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300037/
https://www.ncbi.nlm.nih.gov/pubmed/25629087
http://dx.doi.org/10.1155/2015/808314
work_keys_str_mv AT mouchtourisnikolaos managementofcerebralcavernousmalformationsfromdiagnosistotreatment
AT chalouhinohra managementofcerebralcavernousmalformationsfromdiagnosistotreatment
AT chitaleameet managementofcerebralcavernousmalformationsfromdiagnosistotreatment
AT starkerobertm managementofcerebralcavernousmalformationsfromdiagnosistotreatment
AT tjoumakarisstavropoulai managementofcerebralcavernousmalformationsfromdiagnosistotreatment
AT rosenwasserroberth managementofcerebralcavernousmalformationsfromdiagnosistotreatment
AT jabbourpascalm managementofcerebralcavernousmalformationsfromdiagnosistotreatment