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Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment
Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300037/ https://www.ncbi.nlm.nih.gov/pubmed/25629087 http://dx.doi.org/10.1155/2015/808314 |
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author | Mouchtouris, Nikolaos Chalouhi, Nohra Chitale, Ameet Starke, Robert M. Tjoumakaris, Stavropoula I. Rosenwasser, Robert H. Jabbour, Pascal M. |
author_facet | Mouchtouris, Nikolaos Chalouhi, Nohra Chitale, Ameet Starke, Robert M. Tjoumakaris, Stavropoula I. Rosenwasser, Robert H. Jabbour, Pascal M. |
author_sort | Mouchtouris, Nikolaos |
collection | PubMed |
description | Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics. |
format | Online Article Text |
id | pubmed-4300037 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43000372015-01-27 Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment Mouchtouris, Nikolaos Chalouhi, Nohra Chitale, Ameet Starke, Robert M. Tjoumakaris, Stavropoula I. Rosenwasser, Robert H. Jabbour, Pascal M. ScientificWorldJournal Review Article Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics. Hindawi Publishing Corporation 2015 2015-01-05 /pmc/articles/PMC4300037/ /pubmed/25629087 http://dx.doi.org/10.1155/2015/808314 Text en Copyright © 2015 Nikolaos Mouchtouris et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Mouchtouris, Nikolaos Chalouhi, Nohra Chitale, Ameet Starke, Robert M. Tjoumakaris, Stavropoula I. Rosenwasser, Robert H. Jabbour, Pascal M. Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
title | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
title_full | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
title_fullStr | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
title_full_unstemmed | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
title_short | Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment |
title_sort | management of cerebral cavernous malformations: from diagnosis to treatment |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300037/ https://www.ncbi.nlm.nih.gov/pubmed/25629087 http://dx.doi.org/10.1155/2015/808314 |
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