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High-throughput profiling of point mutations across the HIV-1 genome

BACKGROUND: The HIV-1 pandemic is not the result of a static pathogen but a large genetically diverse and dynamic viral population. The virus is characterized by a highly mutable genome rendering efforts to design a universal vaccine a significant challenge and drives the emergence of drug resistant...

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Detalles Bibliográficos
Autores principales: Al-Mawsawi, Laith Q, Wu, Nicholas C, Olson, C Anders, Shi, Vivian Cai, Qi, Hangfei, Zheng, Xiaojuan, Wu, Ting-Ting, Sun, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300175/
https://www.ncbi.nlm.nih.gov/pubmed/25522661
http://dx.doi.org/10.1186/s12977-014-0124-6