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Variable Expression of PIK3R3 and PTEN in Ewing Sarcoma Impacts Oncogenic Phenotypes

Ewing Sarcoma is an aggressive malignancy of bone and soft tissue affecting children and young adults. Ewing Sarcoma is driven by EWS/Ets fusion oncoproteins, which cause widespread alterations in gene expression in the cell. Dysregulation of receptor tyrosine kinase signaling, particularly involvin...

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Detalles Bibliográficos
Autores principales:	Niemeyer, Brian F., Parrish, Janet K., Spoelstra, Nicole S., Joyal, Teresa, Richer, Jennifer K., Jedlicka, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300218/ https://www.ncbi.nlm.nih.gov/pubmed/25603314 http://dx.doi.org/10.1371/journal.pone.0116895

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