Emerging Role of Linker Histone Variant H1x as a Biomarker with Prognostic Value in Astrocytic Gliomas. A Multivariate Analysis including Trimethylation of H3K9 and H4K20

Although epigenetic alterations play an essential role in gliomagenesis, the relevance of aberrant histone modifications and the respective enzymes has not been clarified. Experimental data implicates histone H3 lysine (K) methyltransferases SETDB1 and SUV39H1 into glioma pathobiology, whereas linke...

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Detalles Bibliográficos
Autores principales: Sepsa, Athanasia, Levidou, Georgia, Gargalionis, Antonis, Adamopoulos, Christos, Spyropoulou, Anastasia, Dalagiorgou, Georgia, Thymara, Irene, Boviatsis, Efstathios, Themistocleous, Marios S., Petraki, Kalliopi, Vrettakos, George, Samaras, Vassilis, Zisakis, Athanassios, Patsouris, Efstratios, Piperi, Christina, Korkolopoulou, Penelope
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300227/
https://www.ncbi.nlm.nih.gov/pubmed/25602259
http://dx.doi.org/10.1371/journal.pone.0115101

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