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CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages
BACKGROUND: Inhibition of metastasis through upregulation of immune surveillance is a major purpose of chemokine gene therapy. In this study, we focused on a membrane-bound chemokine CXCL16, which has shown a correlation with a good prognosis for colorectal cancer (CRC) patients. METHODS: We generat...
Autores principales: | Kee, Ji-Ye, Ito, Aya, Hojo, Shozo, Hashimoto, Isaya, Igarashi, Yoshiko, Tsuneyama, Koichi, Tsukada, Kazuhiro, Irimura, Tatsuro, Shibahara, Naotoshi, Takasaki, Ichiro, Inujima, Akiko, Nakayama, Takashi, Yoshie, Osamu, Sakurai, Hiroaki, Saiki, Ikuo, Koizumi, Keiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300614/ https://www.ncbi.nlm.nih.gov/pubmed/25495942 http://dx.doi.org/10.1186/1471-2407-14-949 |
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