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Signaling pathway STAT1 is strongly activated by IFN-β in the pathogenesis of osteoporosis
BACKGROUND: Despite extensive research, the underlying pathological mechanisms of osteoporosis are not completely understood. Recent studies have indicated a distinct role for the IFN-β/STAT1 pathway in bone metabolism. An inhibitory effect of IFN-β on osteoclastogenesis has been detected and STAT1/...
Autores principales: | Seeliger, Claudine, Schyschka, Lilianna, Kronbach, Zienab, Wottge, Angela, van Griensven, Martijn, Wildemann, Britt, Vester, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300729/ https://www.ncbi.nlm.nih.gov/pubmed/25563300 http://dx.doi.org/10.1186/s40001-014-0074-4 |
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