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Acute Osteoclast Activity following Subchondral Drilling Is Promoted by Chitosan and Associated with Improved Cartilage Repair Tissue Integration

OBJECTIVE: Cartilage-bone integration is an important functional end point of cartilage repair therapy, but little is known about how to promote integration. We tested the hypothesis that chitosan-stabilized blood clot implant elicits osteoclasts to drilled cartilage defects and promotes repair and...

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Detalles Bibliográficos
Autores principales: Chen, G., Sun, J., Lascau-Coman, V., Chevrier, A., Marchand, C., Hoemann, Caroline D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300782/
https://www.ncbi.nlm.nih.gov/pubmed/26069578
http://dx.doi.org/10.1177/1947603510381096