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Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years

BACKGROUND: Microfracture (MFX) is frequently used to treat deep cartilage defects in the ankle; however, the data on repair tissue (RT) quality after MFX are very limited at this time. T2-mapping at 3 T has been optimized for the ankle and can be used to noninvasively evaluate cartilage collagen an...

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Autores principales: Domayer, S.E., Welsch, G.H., Stelzeneder, D., Hirschfeld, C., Quirbach, S., Nehrer, S., Dorotka, R., Mamisch, T.C., Trattnig, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300787/
https://www.ncbi.nlm.nih.gov/pubmed/26069571
http://dx.doi.org/10.1177/1947603510380901
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author Domayer, S.E.
Welsch, G.H.
Stelzeneder, D.
Hirschfeld, C.
Quirbach, S.
Nehrer, S.
Dorotka, R.
Mamisch, T.C.
Trattnig, S.
author_facet Domayer, S.E.
Welsch, G.H.
Stelzeneder, D.
Hirschfeld, C.
Quirbach, S.
Nehrer, S.
Dorotka, R.
Mamisch, T.C.
Trattnig, S.
author_sort Domayer, S.E.
collection PubMed
description BACKGROUND: Microfracture (MFX) is frequently used to treat deep cartilage defects in the ankle; however, the data on repair tissue (RT) quality after MFX are very limited at this time. T2-mapping at 3 T has been optimized for the ankle and can be used to noninvasively evaluate cartilage collagen and water content. The aim of this study was to determine if the RT after MFX in the ankle had T2 properties similar to the adjacent reference cartilage (RC). METHODS: Fourteen cases after MFX in the ankle were assessed with morphological MRI and T2-mapping at 3 T. The American Orthopaedic Foot and Ankle Society (AOFAS) score and a modified Cinicinnati Knee Rating System rating were used to evaluate the clinical outcome. The MRI protocol included a 3-dimensional sequence and a proton-density sequence for morphological evaluation and a multiecho spin echo sequence for T2-mapping. Region of interest analyses were carried out in accordance with the morphological images to ensure complete coverage of the defect site. RESULTS: Both clinical scores demonstrated significant improvement at the time of the MR examination (P < 0.001). RT T2 was 49.3 ± 10.1 (range, 35.7-69.3) milliseconds, and RC T2 was 49.9 ± 8.2 (range, 38.4-63.7) milliseconds (P = 0.838). Relative T2 (rT2) was 1.00 ± 0.20 (range, 0.72-1.36). CONCLUSION: MFX in the ankle can provide RT with T2 properties similar to adjacent cartilage.
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spelling pubmed-43007872015-06-11 Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years Domayer, S.E. Welsch, G.H. Stelzeneder, D. Hirschfeld, C. Quirbach, S. Nehrer, S. Dorotka, R. Mamisch, T.C. Trattnig, S. Cartilage Original Articles BACKGROUND: Microfracture (MFX) is frequently used to treat deep cartilage defects in the ankle; however, the data on repair tissue (RT) quality after MFX are very limited at this time. T2-mapping at 3 T has been optimized for the ankle and can be used to noninvasively evaluate cartilage collagen and water content. The aim of this study was to determine if the RT after MFX in the ankle had T2 properties similar to the adjacent reference cartilage (RC). METHODS: Fourteen cases after MFX in the ankle were assessed with morphological MRI and T2-mapping at 3 T. The American Orthopaedic Foot and Ankle Society (AOFAS) score and a modified Cinicinnati Knee Rating System rating were used to evaluate the clinical outcome. The MRI protocol included a 3-dimensional sequence and a proton-density sequence for morphological evaluation and a multiecho spin echo sequence for T2-mapping. Region of interest analyses were carried out in accordance with the morphological images to ensure complete coverage of the defect site. RESULTS: Both clinical scores demonstrated significant improvement at the time of the MR examination (P < 0.001). RT T2 was 49.3 ± 10.1 (range, 35.7-69.3) milliseconds, and RC T2 was 49.9 ± 8.2 (range, 38.4-63.7) milliseconds (P = 0.838). Relative T2 (rT2) was 1.00 ± 0.20 (range, 0.72-1.36). CONCLUSION: MFX in the ankle can provide RT with T2 properties similar to adjacent cartilage. SAGE Publications 2011-01 /pmc/articles/PMC4300787/ /pubmed/26069571 http://dx.doi.org/10.1177/1947603510380901 Text en © The Author(s) 2011
spellingShingle Original Articles
Domayer, S.E.
Welsch, G.H.
Stelzeneder, D.
Hirschfeld, C.
Quirbach, S.
Nehrer, S.
Dorotka, R.
Mamisch, T.C.
Trattnig, S.
Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years
title Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years
title_full Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years
title_fullStr Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years
title_full_unstemmed Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years
title_short Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years
title_sort microfracture in the ankle: clinical results and mri with t2-mapping at 3.0 t after 1 to 8 years
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300787/
https://www.ncbi.nlm.nih.gov/pubmed/26069571
http://dx.doi.org/10.1177/1947603510380901
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