Cargando…

Characterization of an Ex vivo Femoral Head Model Assessed by Markers of Bone and Cartilage Turnover

OBJECTIVE: The pathophysiology of osteoarthritis involves the whole joint and is characterized by cartilage degradation and altered subchondral bone turnover. At present, there is a need for biological models that allow investigation of the interactions between the key cellular players in bone/carti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Madsen, Suzi Hoegh, Goettrup, Anne Sofie, Thomsen, Gedske, Christensen, Søren Tvorup, Schultz, Nikolaj, Henriksen, Kim, Bay-Jensen, Anne-Christine, Karsdal, Morten Asser
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300811/ https://www.ncbi.nlm.nih.gov/pubmed/26069585 http://dx.doi.org/10.1177/1947603510383855

Ejemplares similares

Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo
por: Reker, Ditte, et al.
Publicado: (2017)

The Anti-ADAMTS-5 Nanobody(®) M6495 Protects Cartilage Degradation Ex Vivo
por: Siebuhr, Anne Sofie, et al.
Publicado: (2020)

Cartilage Turnover Reflected by Metabolic Processing of Type II Collagen: A Novel Marker of Anabolic Function in Chondrocytes
por: Gudmann, Natasja Stæhr, et al.
Publicado: (2014)

The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases
por: Sun, Shu, et al.
Publicado: (2014)

Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis
por: Siebuhr, Anne Sofie, et al.
Publicado: (2012)

The Inhibitory Effect of Salmon Calcitonin on Tri-Iodothyronine Induction of Early Hypertrophy in Articular Cartilage
por: Chen-An, Pingping, et al.
Publicado: (2012)

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity
por: Karsdal, Morten A, et al.
Publicado: (2008)

Serological Biomarkers of Joint Tissue Turnover Predict Tocilizumab Response at Baseline
por: Bay-Jensen, Anne C., et al.
Publicado: (2014)

Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments
por: Wang, Bijue, et al.
Publicado: (2009)

Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis
por: Bihlet, Asger Reinstrup, et al.
Publicado: (2019)

Serum biomarkers of collagen turnover as potential diagnostic tools in diffuse systemic sclerosis: A cross-sectional study
por: Juhl, Pernille, et al.
Publicado: (2018)

Neo-Epitopes—Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis
por: Maijer, Karen I., et al.
Publicado: (2016)

The Efficacy and Safety of Multiple Dose Regimens of Kudzu (Pueraria lobata) Root Extract on Bone and Cartilage Turnover and Menopausal Symptoms
por: Bihlet, Asger Reinstrup, et al.
Publicado: (2021)

Synovitis biomarkers: ex vivo characterization of three biomarkers for identification of inflammatory osteoarthritis
por: Kjelgaard-Petersen, Cecilie, et al.
Publicado: (2015)

Collagen turnover profiles in chronic kidney disease
por: Rasmussen, Daniel Guldager Kring, et al.
Publicado: (2019)

Evaluation of serum ARGS neoepitope as an osteoarthritis biomarker using a standardized model for exercise-induced cartilage extra cellular matrix turnover
por: Bjerre-Bastos, Jonathan J., et al.
Publicado: (2020)

The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile
por: Larsen, Anna Thorsø, et al.
Publicado: (2021)

Effect of n-3 PUFA on extracellular matrix protein turnover in patients with psoriatic arthritis: a randomized, double-blind, placebo-controlled trial
por: Holm Nielsen, Signe, et al.
Publicado: (2021)

Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation
por: He, Yi, et al.
Publicado: (2014)

The minor collagens in articular cartilage
por: Luo, Yunyun, et al.
Publicado: (2017)

Ulcerative colitis, Crohn’s disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn’s disease
por: Mortensen, Joachim Høg, et al.
Publicado: (2017)

Dermal fibroblasts have different extracellular matrix profiles induced by TGF-β, PDGF and IL-6 in a model for skin fibrosis
por: Juhl, Pernille, et al.
Publicado: (2020)

Diagnosis of Osteoarthritis by Cartilage Surface Smoothness Quantified Automatically from Knee MRI
por: Tummala, Sudhakar, et al.
Publicado: (2011)

Is radiographic progression in radiographic axial spondyloarthritis related to matrix metalloproteinase degradation of extracellular matrix?
por: Siebuhr, Anne Sofie, et al.
Publicado: (2018)

Extracellular matrix protein turnover markers are associated with axial spondyloarthritis—a comparison with postpartum women and other non-axial spondyloarthritis controls with or without back pain
por: Port, Helena, et al.
Publicado: (2022)

The Impact of Exposure Profile on the Efficacy of Dual Amylin and Calcitonin Receptor Agonist Therapy
por: Sonne, Nina, et al.
Publicado: (2022)

Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD
por: Bihlet, Asger Reinstrup, et al.
Publicado: (2017)

Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
por: Veidal, Sanne Skovgård, et al.
Publicado: (2010)

Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia
por: Tang, Man-Hung Eric, et al.
Publicado: (2020)

Blood and urine biomarkers in osteoarthritis – an update on cartilage associated type II collagen and aggrecan markers
por: Bay-Jensen, Anne C., et al.
Publicado: (2022)

GPDPLQ(1237)—A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro
por: Löfvall, Henrik, et al.
Publicado: (2019)

Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model
por: Veidal, Sanne Skovgård, et al.
Publicado: (2012)

Chondrocyte activity is increased in psoriatic arthritis and axial spondyloarthritis
por: Gudmann, Natasja Stæhr, et al.
Publicado: (2016)

Development of a Novel Enzyme-Linked Immunosorbent Assay Targeting a Neo-Epitope Generated by Cathepsin-Mediated Turnover of Type III Collagen and Its Application in Chronic Obstructive Pulmonary Disease
por: Rasmussen, Daniel Guldager Kring, et al.
Publicado: (2017)

Fibroblasts are not just fibroblasts: clear differences between dermal and pulmonary fibroblasts’ response to fibrotic growth factors
por: Madsen, Sofie Falkenløve, et al.
Publicado: (2023)

The Potential of Pathological Protein Fragmentation in Blood-Based Biomarker Development for Dementia – With Emphasis on Alzheimer’s Disease
por: Inekci, Dilek, et al.
Publicado: (2015)

A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation
por: Luo, Yunyun, et al.
Publicado: (2018)

Procollagen type I N-terminal propeptide (PINP) is a marker for fibrogenesis in bile duct ligation-induced fibrosis in rats
por: Veidal, Sanne Skovgård, et al.
Publicado: (2010)

Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor
por: Hansen, Niels Ulrik Brandt, et al.
Publicado: (2016)

Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
por: Vesterhus, Mette, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lbk8ivem70bhmvv6cn2vl8isav