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Substrate binding on the APC/C occurs between the co-activator CDH1 and the processivity factor DOC1

The anaphase–promoting complex/cyclosome (APC/C) is a 22 S ubiquitin ligase complex that initiates chromosome segregation and mitotic exit. We have used biochemical and electron microscopic analyses of Saccharomyces cerevisiae and human APC/C to address how the APC/C subunit Doc1 contributes to recr...

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Detalles Bibliográficos
Autores principales:	Buschhorn, Bettina A., Petzold, Georg, Galova, Marta, Dube, Prakash, Kraft, Claudine, Herzog, Franz, Stark, Holger, Peters, Jan–Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300845/ https://www.ncbi.nlm.nih.gov/pubmed/21186364 http://dx.doi.org/10.1038/nsmb.1979

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