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Molecular and evolutionary insights into the structural organization of cation chloride cotransporters
Cation chloride cotransporters (CCC) play an essential role for neuronal chloride homeostasis. K(+)-Cl(−) cotransporter (KCC2), is the principal Cl(−)-extruder, whereas Na(+)-K(+)-Cl(−) cotransporter (NKCC1), is the major Cl(−)-uptake mechanism in many neurons. As a consequence, the action of the in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301019/ https://www.ncbi.nlm.nih.gov/pubmed/25653592 http://dx.doi.org/10.3389/fncel.2014.00470 |