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Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration

Merkel cell carcinoma (MCC) is an aggressive skin cancer of neuroendocrine origin with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) causes the majority of MCC cases due to the expression of the MCPyV small and large tumor antigens (ST and LT, respectively). Altho...

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Detalles Bibliográficos
Autores principales: Knight, Laura M., Stakaityte, Gabriele, Wood, Jennifer, J., Abdul-Sada, Hussein, Griffiths, David A., Howell, Gareth J., Wheat, Rachel, Blair, G. Eric, Steven, Neil M., Macdonald, Andrew, Blackbourn, David J., Whitehouse, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301106/
https://www.ncbi.nlm.nih.gov/pubmed/25320307
http://dx.doi.org/10.1128/JVI.02317-14