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Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration
Merkel cell carcinoma (MCC) is an aggressive skin cancer of neuroendocrine origin with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) causes the majority of MCC cases due to the expression of the MCPyV small and large tumor antigens (ST and LT, respectively). Altho...
Autores principales: | Knight, Laura M., Stakaityte, Gabriele, Wood, Jennifer, J., Abdul-Sada, Hussein, Griffiths, David A., Howell, Gareth J., Wheat, Rachel, Blair, G. Eric, Steven, Neil M., Macdonald, Andrew, Blackbourn, David J., Whitehouse, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301106/ https://www.ncbi.nlm.nih.gov/pubmed/25320307 http://dx.doi.org/10.1128/JVI.02317-14 |
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