A general mechanism for competitor-induced dissociation of molecular complexes

The kinetic stability of non-covalent macromolecular complexes controls many biological phenomena. Here we find that physical models of complex dissociation predict that competitor molecules will in general accelerate the breakdown of isolated bimolecular complexes by occluding rapid rebinding of th...

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Detalles Bibliográficos
Autores principales: Paramanathan, Thayaparan, Reeves, Daniel, Friedman, Larry J., Kondev, Jane, Gelles, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301414/
https://www.ncbi.nlm.nih.gov/pubmed/25342513
http://dx.doi.org/10.1038/ncomms6207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301414/
https://www.ncbi.nlm.nih.gov/pubmed/25342513
http://dx.doi.org/10.1038/ncomms6207

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