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TP53-induced glycolysis and apoptosis regulator promotes proliferation and invasiveness of nasopharyngeal carcinoma cells

The TP53-induced glycolysis and apoptosis regulator (TIGAR) is the protein product of the p53 target gene, C12orf5. TIGAR blocks glycolysis and promotes cellular metabolism via the pentose phosphate pathway; it promotes the production of cellular nicotinamide adenine dinucleotide phosphate (NADPH),...

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Detalles Bibliográficos
Autores principales: WONG, ELAINE YUE LING, WONG, SZE-CHUEN CESAR, CHAN, CHARLES MING LOK, LAM, EMILY KAI YEE, HO, LOUISA YEUNG, LAU, CECILIA PIK YUK, AU, THOMAS CHI CHUEN, CHAN, AMANDA KIT CHING, TSANG, CHI MAN, TSAO, SAI WAH, LUI, VIVIAN WAI YAN, CHAN, ANTHONY TAK CHEUNG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301475/
https://www.ncbi.nlm.nih.gov/pubmed/25621025
http://dx.doi.org/10.3892/ol.2014.2797