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Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
The aim of the present study was to analyse clinical data obtained from lung cancer patients, including the initial clinical symptoms upon diagnosis, duration of patient delay in presenting to a doctor, lung cancer stage, treatment strategy and prognosis. A retrospective analysis was conducted of th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301476/ https://www.ncbi.nlm.nih.gov/pubmed/25621024 http://dx.doi.org/10.3892/ol.2014.2777 |
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author | SHAO, QIAN LI, JIANBIN LI, FENGXIANG WANG, SUZHEN WANG, WEI LIU, SHANSHAN ZHANG, YINGJIE |
author_facet | SHAO, QIAN LI, JIANBIN LI, FENGXIANG WANG, SUZHEN WANG, WEI LIU, SHANSHAN ZHANG, YINGJIE |
author_sort | SHAO, QIAN |
collection | PubMed |
description | The aim of the present study was to analyse clinical data obtained from lung cancer patients, including the initial clinical symptoms upon diagnosis, duration of patient delay in presenting to a doctor, lung cancer stage, treatment strategy and prognosis. A retrospective analysis was conducted of the clinical features of 1,168 lung cancer patients who were initially diagnosed and treated at the Tumor Hospital of Shandong Province (Jinan, China) in 2009. The Kaplan-Meier method and multivariate Cox regression analysis were performed to analyse the influence of gender, age, predominant symptoms, histopathological or cytological type and clinical staging on the overall patient survival. The follow-up rate of the present study was 92.4%, and the 1-, 2- and 3-year survival rates were 80.4, 44.9 and 15.8%, respectively. Multivariate analysis demonstrated that the patient age, extent of the tumour (T stage), extent of lymph node spread (N stage), overall clinical stage and treatment strategy were independent risk factors associated with patient survival. The present study identified that the initial symptoms of lung cancer varied, patient delay was long, the lung cancer cases were diagnosed in late clinical stages and the prognosis was poor. |
format | Online Article Text |
id | pubmed-4301476 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-43014762015-01-23 Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients SHAO, QIAN LI, JIANBIN LI, FENGXIANG WANG, SUZHEN WANG, WEI LIU, SHANSHAN ZHANG, YINGJIE Oncol Lett Articles The aim of the present study was to analyse clinical data obtained from lung cancer patients, including the initial clinical symptoms upon diagnosis, duration of patient delay in presenting to a doctor, lung cancer stage, treatment strategy and prognosis. A retrospective analysis was conducted of the clinical features of 1,168 lung cancer patients who were initially diagnosed and treated at the Tumor Hospital of Shandong Province (Jinan, China) in 2009. The Kaplan-Meier method and multivariate Cox regression analysis were performed to analyse the influence of gender, age, predominant symptoms, histopathological or cytological type and clinical staging on the overall patient survival. The follow-up rate of the present study was 92.4%, and the 1-, 2- and 3-year survival rates were 80.4, 44.9 and 15.8%, respectively. Multivariate analysis demonstrated that the patient age, extent of the tumour (T stage), extent of lymph node spread (N stage), overall clinical stage and treatment strategy were independent risk factors associated with patient survival. The present study identified that the initial symptoms of lung cancer varied, patient delay was long, the lung cancer cases were diagnosed in late clinical stages and the prognosis was poor. D.A. Spandidos 2015-02 2014-12-08 /pmc/articles/PMC4301476/ /pubmed/25621024 http://dx.doi.org/10.3892/ol.2014.2777 Text en Copyright © 2015, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles SHAO, QIAN LI, JIANBIN LI, FENGXIANG WANG, SUZHEN WANG, WEI LIU, SHANSHAN ZHANG, YINGJIE Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
title | Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
title_full | Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
title_fullStr | Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
title_full_unstemmed | Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
title_short | Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
title_sort | clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301476/ https://www.ncbi.nlm.nih.gov/pubmed/25621024 http://dx.doi.org/10.3892/ol.2014.2777 |
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