Cargando…

Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients

The aim of the present study was to analyse clinical data obtained from lung cancer patients, including the initial clinical symptoms upon diagnosis, duration of patient delay in presenting to a doctor, lung cancer stage, treatment strategy and prognosis. A retrospective analysis was conducted of th...

Descripción completa

Detalles Bibliográficos
Autores principales: SHAO, QIAN, LI, JIANBIN, LI, FENGXIANG, WANG, SUZHEN, WANG, WEI, LIU, SHANSHAN, ZHANG, YINGJIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301476/
https://www.ncbi.nlm.nih.gov/pubmed/25621024
http://dx.doi.org/10.3892/ol.2014.2777
_version_ 1782353647952199680
author SHAO, QIAN
LI, JIANBIN
LI, FENGXIANG
WANG, SUZHEN
WANG, WEI
LIU, SHANSHAN
ZHANG, YINGJIE
author_facet SHAO, QIAN
LI, JIANBIN
LI, FENGXIANG
WANG, SUZHEN
WANG, WEI
LIU, SHANSHAN
ZHANG, YINGJIE
author_sort SHAO, QIAN
collection PubMed
description The aim of the present study was to analyse clinical data obtained from lung cancer patients, including the initial clinical symptoms upon diagnosis, duration of patient delay in presenting to a doctor, lung cancer stage, treatment strategy and prognosis. A retrospective analysis was conducted of the clinical features of 1,168 lung cancer patients who were initially diagnosed and treated at the Tumor Hospital of Shandong Province (Jinan, China) in 2009. The Kaplan-Meier method and multivariate Cox regression analysis were performed to analyse the influence of gender, age, predominant symptoms, histopathological or cytological type and clinical staging on the overall patient survival. The follow-up rate of the present study was 92.4%, and the 1-, 2- and 3-year survival rates were 80.4, 44.9 and 15.8%, respectively. Multivariate analysis demonstrated that the patient age, extent of the tumour (T stage), extent of lymph node spread (N stage), overall clinical stage and treatment strategy were independent risk factors associated with patient survival. The present study identified that the initial symptoms of lung cancer varied, patient delay was long, the lung cancer cases were diagnosed in late clinical stages and the prognosis was poor.
format Online
Article
Text
id pubmed-4301476
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-43014762015-01-23 Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients SHAO, QIAN LI, JIANBIN LI, FENGXIANG WANG, SUZHEN WANG, WEI LIU, SHANSHAN ZHANG, YINGJIE Oncol Lett Articles The aim of the present study was to analyse clinical data obtained from lung cancer patients, including the initial clinical symptoms upon diagnosis, duration of patient delay in presenting to a doctor, lung cancer stage, treatment strategy and prognosis. A retrospective analysis was conducted of the clinical features of 1,168 lung cancer patients who were initially diagnosed and treated at the Tumor Hospital of Shandong Province (Jinan, China) in 2009. The Kaplan-Meier method and multivariate Cox regression analysis were performed to analyse the influence of gender, age, predominant symptoms, histopathological or cytological type and clinical staging on the overall patient survival. The follow-up rate of the present study was 92.4%, and the 1-, 2- and 3-year survival rates were 80.4, 44.9 and 15.8%, respectively. Multivariate analysis demonstrated that the patient age, extent of the tumour (T stage), extent of lymph node spread (N stage), overall clinical stage and treatment strategy were independent risk factors associated with patient survival. The present study identified that the initial symptoms of lung cancer varied, patient delay was long, the lung cancer cases were diagnosed in late clinical stages and the prognosis was poor. D.A. Spandidos 2015-02 2014-12-08 /pmc/articles/PMC4301476/ /pubmed/25621024 http://dx.doi.org/10.3892/ol.2014.2777 Text en Copyright © 2015, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
SHAO, QIAN
LI, JIANBIN
LI, FENGXIANG
WANG, SUZHEN
WANG, WEI
LIU, SHANSHAN
ZHANG, YINGJIE
Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
title Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
title_full Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
title_fullStr Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
title_full_unstemmed Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
title_short Clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
title_sort clinical investigation into the initial diagnosis and treatment of 1,168 lung cancer patients
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301476/
https://www.ncbi.nlm.nih.gov/pubmed/25621024
http://dx.doi.org/10.3892/ol.2014.2777
work_keys_str_mv AT shaoqian clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients
AT lijianbin clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients
AT lifengxiang clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients
AT wangsuzhen clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients
AT wangwei clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients
AT liushanshan clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients
AT zhangyingjie clinicalinvestigationintotheinitialdiagnosisandtreatmentof1168lungcancerpatients