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Increased BRAF copy number in lung adenocarcinoma

Point mutation of the BRAF gene is a genetic event that occurs in a subset of lung adenocarcinoma cases. For example, BRAF V600E is a driver mutation that can be effectively targeted using selective BRAF and/or MEK inhibitors. The present study hypothesized that an increase in BRAF copy number may b...

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Detalles Bibliográficos
Autores principales:	SASAKI, HIDEFUMI, MAEKAWA, MASAHIKO, TATEMATSU, TSUTOMU, OKUDA, KATSUHIRO, MORIYAMA, SATORU, YANO, MOTOKI, FUJII, YOSHITAKA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301492/ https://www.ncbi.nlm.nih.gov/pubmed/25621040 http://dx.doi.org/10.3892/ol.2014.2719

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