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Gene expression changes during retinal development and rod specification

PURPOSE: Retinitis pigmentosa (RP) typically results from individual mutations in any one of >70 genes that cause rod photoreceptor cells to degenerate prematurely, eventually resulting in blindness. Gene therapies targeting individual RP genes have shown efficacy at clinical trial; however, thes...

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Detalles Bibliográficos
Autores principales: Mansergh, Fiona C., Carrigan, Matthew, Hokamp, Karsten, Farrar, G. Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301594/
https://www.ncbi.nlm.nih.gov/pubmed/25678762