A Genome-Wide Investigation of MicroRNA Expression Identifies Biologically-Meaningful MicroRNAs That Distinguish between High-Risk and Low-Risk Intraductal Papillary Mucinous Neoplasms of the Pancreas

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic ductal adenocarcinoma (PDAC) precursors. Differentiating between high-risk IPMNs that warrant surgical resection and low-risk IPMNs that can be monitored is a significant clinical problem, and we sought to discover a panel o...

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Detalles Bibliográficos
Autores principales: Permuth-Wey, Jennifer, Chen, Y. Ann, Fisher, Kate, McCarthy, Susan, Qu, Xiaotao, Lloyd, Mark C., Kasprzak, Agnieszka, Fournier, Michelle, Williams, Vonetta L., Ghia, Kavita M., Yoder, Sean J., Hall, Laura, Georgeades, Christina, Olaoye, Funmilayo, Husain, Kazim, Springett, Gregory M., Chen, Dung-Tsa, Yeatman, Timothy, Centeno, Barbara Ann, Klapman, Jason, Coppola, Domenico, Malafa, Mokenge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301643/
https://www.ncbi.nlm.nih.gov/pubmed/25607660
http://dx.doi.org/10.1371/journal.pone.0116869

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