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An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss

BACKGROUND: Environmental factors can influence obesity by epigenetic mechanisms. Adipose tissue plays a key role in obesity-related metabolic dysfunction, and gastric bypass provides a model to investigate obesity and weight loss in humans. RESULTS: Here, we investigate DNA methylation in adipose t...

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Detalles Bibliográficos
Autores principales:	Benton, Miles C, Johnstone, Alice, Eccles, David, Harmon, Brennan, Hayes, Mark T, Lea, Rod A, Griffiths, Lyn, Hoffman, Eric P, Stubbs, Richard S, Macartney-Coxson, Donia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301800/ https://www.ncbi.nlm.nih.gov/pubmed/25651499 http://dx.doi.org/10.1186/s13059-014-0569-x

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