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Functional Comparison of Induced Pluripotent Stem Cell- and Blood-Derived GPIIbIIIa Deficient Platelets
Human induced pluripotent stem cells (hiPSCs) represent a versatile tool to model genetic diseases and are a potential source for cell transfusion therapies. However, it remains elusive to which extent patient-specific hiPSC-derived cells functionally resemble their native counterparts. Here, we gen...
Autores principales: | Orban, Mathias, Goedel, Alexander, Haas, Jessica, Sandrock-Lang, Kirstin, Gärtner, Florian, Jung, Christian Billy, Zieger, Barbara, Parrotta, Elvira, Kurnik, Karin, Sinnecker, Daniel, Wanner, Gerhard, Laugwitz, Karl-Ludwig, Massberg, Steffen, Moretti, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301811/ https://www.ncbi.nlm.nih.gov/pubmed/25607928 http://dx.doi.org/10.1371/journal.pone.0115978 |
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