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Catalysis by the Tumor-Suppressor Enzymes PTEN and PTEN-L
Phosphatase and tensin homologue deleted from chromosome ten (PTEN) is a lipid phosphatase tumor suppressor that is lost or inactivated in most human tumors. The enzyme catalyzes the hydrolysis of phosphatidylinositol-(3,4,5)-trisphosphate (PIP(3)) to form phosphatidylinositol-(4,5)-bisphosphate (PI...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301912/ https://www.ncbi.nlm.nih.gov/pubmed/25607987 http://dx.doi.org/10.1371/journal.pone.0116898 |