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Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype
BACKGROUND: Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor that acts against receptors for vascular endothelial growth factor and platelet-derived growth factor. Common toxicities of sunitinib treatment include hypertension, hand–foot syndrome, vomiting, and diarrhea, and the propo...
Autores principales: | Miura, Yuji, Imamura, Chiyo K, Fukunaga, Koya, Katsuyama, Yoshihiko, Suyama, Koichi, Okaneya, Toshikazu, Mushiroda, Taisei, Ando, Yuichi, Takano, Toshimi, Tanigawara, Yusuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301945/ https://www.ncbi.nlm.nih.gov/pubmed/25515134 http://dx.doi.org/10.1186/1471-2407-14-964 |
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